Photoacoustic Imaging of Epilepsy

Abstract

This research is aimed at developing a new imaging approach, called Photoacoustic tomography (PAT) , for non-invasively tracking dynamical changes during seizure occurrence. The project will develop imaging hardware and software, and conduct phantom/in vivo experiments to achieve the proposed goals. During the third year of this project, we have developed the advanced boundary conditions scheme, and implemented the 3D reconstruction codes and their parallelization which allowed efficient high performance PAT image reconstruction. We have conducted simulation and phantom experiments that confirmed our software enhancement. We have performed extensive in vivo experiments using the rat epilepsy model to evaluate the PAT system we developed in this project. The results show that we were able to image the functional anatomy of epileptic foci noninvasively and in real time at a spatial resolution of ~150 m.

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 2012
Accession Number
ADA587641

Entities

People

  • Huabei Jiang

Organizations

  • University of Florida

Tags

Communities of Interest

  • Biomedical
  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Acoustic Properties
  • Arteries
  • Brain
  • Central Processing Units
  • Detectors
  • Epilepsy
  • Image Reconstruction
  • Imaging Techniques
  • Medical Personnel
  • Neurosciences
  • Optical Properties
  • Photoacoustic Tomography
  • Seizures
  • Tomography

Fields of Study

  • Medicine
  • Physics

Readers

  • Canadian European Scientific Immigration and Epilepsy Clearance Studies
  • Computational Fluid Dynamics (CFD)
  • Medical Imaging.