Preparation, Delivery, and Evaluation of Picomole Vapor Standards

Abstract

A method is described for the modification and use of a gas chromatograph heated inlet for the preparation of trace vapor reference standards. A conventional GC-MS is used to validate the prepared vapor standards and an evaluation is provided on the reproducibility of replicate measurements made from a single sample as well as individual measurements made between replicate samples. The described method is applied to the preparation of single component trace organic vapors, complex vapor mixtures (containing greater than 10 components over a concentration range spanning four orders of magnitude), and low vapor pressure analytes, which are solids under ambient conditions (e.g., ferrocene). Results demonstrate delivery of picomole quantities of single component organic vapors with a reproducibility of ca. 1% RSD.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Jul 10, 2013
Accession Number
ADA588069

Entities

People

  • Christopher J. Katilie
  • Duane A. Rogers
  • Kevin Johnson

Organizations

  • United States Naval Research Laboratory

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Alkanes
  • Chemical Reactions
  • Chemical Synthesis
  • Chemistry
  • Chlorides
  • Detection
  • Detectors
  • Mass Spectrometry
  • Materials
  • Measurement
  • Organic Chemistry
  • Organic Compounds
  • Standards
  • Training
  • Training Devices
  • Vapor Pressure
  • Volatile Organic Compounds

Readers

  • Analytical Chemistry