Molecular Innovations Toward Theranostics of Aggressive Prostate Cancer

Abstract

The efforts during this period divide between dendrimer preparation, peptide design and preparation, and the exploration of conjugation chemistries. Alkyne-functionalized dendrimers over many generations have been successfully prepared. Therapeutic peptides have been designed, prepared, and submitted to the co-investigators for evaluation. Two conjugation strategies for ligating the therapeutic peptide to the dendrimer platform are being investigated.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2013
Accession Number
ADA590560

Entities

People

  • Eric E Simanek

Organizations

  • Texas Christian University

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • Chemical Reactions
  • Chemistry
  • Demographic Cohorts
  • Dendrimers
  • Department Of Defense
  • Diagnostic Imaging
  • Electronic Mail
  • Information Operations
  • Lead Compounds
  • Materials
  • Platforms
  • Prostate
  • Prostate Cancer
  • Solubility
  • Test And Evaluation

Fields of Study

  • Chemistry

Readers

  • Molecular and Cellular Biochemistry
  • Oncology
  • Polymer Science and Technology