The Role of NF1 in Memory Retrieval
Abstract
We have reported that NF1 affects both immediate memory and long-term memory (LTM), but through different mechanisms in Drosophila (Ho et al., 2007). The goal of this proposal is of studying the hypothesis as to that in long-term memory (LTM), NF1 is specifically involved in mediating memory retrieval, but not required for induction and consolidation. For this purpose, three specific aims are proposed, including (1) to determine NF1 s role in memory retrieval; (2) to identify ligands that activate NF1 for memory retrieval; and (3) to locate the brain region at which NF1-dependent memory retrieval occurs.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 2013
- Accession Number
- ADA591973
Entities
People
- Yi Zhong
Organizations
- Cold Spring Harbor Laboratory