Nano-engineered Drug Combinations for Breast Cancer Treatment

Abstract

We hypothesis that nanoparticles can increase the efficacy of combination therapies for cancer. The project aims to explore nanoparticle-based transport vehicles for effective delivery of two different cancer drugs. In particular, we aim to use two breast cancer drugs, which enhance each other s efficacy and use them as a model drug pair for the development of novel dual-drug nano-therapeutics. The research to date has been focused on extending existing electrohydrodynamic co-jetting technology in the Lahann lab towards the simultaneous release of two independent small molecule drug surrogates.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2013
Accession Number
ADA592056

Entities

People

  • Joerg Lahann

Organizations

  • University of Michigan

Tags

DTIC Thesaurus Topics

  • Alkenes
  • Biological Pigments
  • Breast Cancer
  • Cells
  • Chemical Synthesis
  • Chemistry
  • Combination Therapy
  • Confocal Laser Scanning Microscopy
  • Materials
  • Materials Science
  • Molecules
  • Nanoparticles
  • Neoplasms
  • Polymer Chemistry
  • Polymers
  • Therapy
  • United States

Fields of Study

  • Biology

Readers

  • Nanocomposite Materials Science
  • Oncology (Cancer Research).

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech