A Randomized Clinical Trial of Allopregnanolone for the Treatment of Severe Traumatic Brain Injury

Abstract

There is a strong experimental support fo the concept that allopregnanolone will be safe and have beneficial effects on disability when administered as a treatment following acute traumatic brain injury (TBI). This study will provide initial data on the safety and effectiveness of allopregnanolone in improving neurobehavioral outcome and reducing mortality in adults with moderate and severe TBI.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2012
Accession Number
ADA592941

Entities

People

  • Michael A. Rogawski

Organizations

  • University of California

Tags

DTIC Thesaurus Topics

  • Arteries
  • Biomedical Research
  • Blood
  • Brain Injuries
  • Clinical Trials
  • Contracts
  • Department Of Defense
  • Head Injuries
  • Health Services
  • Institutional Review Board
  • Liquid Chromatography
  • Manufacturing
  • Materials
  • Measurement
  • Medical Personnel
  • Personnel Management
  • Steady State

Fields of Study

  • Medicine

Readers

  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.
  • Neurotrauma and Rehabilitation Medicine.