Disruption of Calcium Homeostasis during Exercise as a Mediator of Bone Metabolism
Abstract
Regulatory approvals, training of research assistants, generation of forms, and creation of the database were completed in Q1 and Q2. Thereafter, the major goals for Year 1 were to complete approximately one-half of Experiment 1 (EXP1) and all of the Experiment 2 Pilot Study (EXP2-pilot). Progress on EXP1 was better than projected, with research visits having been completed for 25 of 28 participants; batched analyses of serum and sweat samples were initiated. Progress was delayed because of 1) limited access to the temperature-controlled facility needed for this EXP1, and 2) hospital shortages of the product required for EXP2-pilot (i.e., calcium chloride or calcium gluconate). The benchmark for moving forward to EXP2 (i.e., 3 successful clamps) is expected to be achieved in October. Therefore, the application for approval of EXP2 will be submitted in Year 2 Q1. One unanticipated problem in EXP2-pilot was reported, but the local IRB subsequently determined that the event was not related to the experimental procedure. Because analyses of samples and data have not yet been completed for EXP1, no abstracts or manuscripts have been generated. The first abstract submission is expected in November 2013.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2013
- Accession Number
- ADA593122
Entities
People
- Wendy M. Kohrt
Organizations
- University of Colorado Boulder