Inhibition of Orthopaedic Implant Infections by Immunomodulatory Effects of Host Defense Peptides

Abstract

Host defense peptides represent a promising new approach to inhibit infection. The anti-infective actions of these peptides are primarily due to their immunomodulatory effects. Since they regulate multiple aspects of the mammalian immune system, host defense peptides are also less likely to induce bacterial resistance than are traditional antibiotics.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2013
Accession Number
ADA594031

Entities

People

  • Edward M. Greenfield

Organizations

  • Case Western Reserve University

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Anti-Bacterial Agents
  • Bacteria
  • Bacterial Infections And Mycoses
  • Biological Sciences
  • Biomedical Research
  • Chemistry
  • Department Of Defense
  • Diseases And Disorders
  • Immune System
  • Infection
  • Inhibition
  • Military Medicine
  • Production
  • Staphylococcus Aureus
  • Titanium Alloys
  • Wound Infections

Fields of Study

  • Medicine

Readers

  • Immunology
  • Trauma Surgery or Emergency Medicine.