Enhancing the Sensitivity of Fluorescence Bronchoscopy for Early Lung Cancer Detection Using a Fluorescent Deoxyglucose Analog
Abstract
The recent development of fluorescently tagged deoxyglucose analog (2-NBDG) has attracted the attention of researchers and clinicians alike for its potential use as a tool in detecting cancer. Although the use of 2-NBDG imaging for cancer diagnosis has been explored in several other organ sites prior to this project, the potential applications of this technique to early lung cancer detection had not been explored. The objective of this study was to monitor both qualitatively and quantitatively 2-NBDG uptake in lung cancer cells and normal cells using fluorescence imaging techniques. Initial results were promising, and this work represents an important first step towards establishing the use of 2-NBDG as a contrast modality for applications in early lung cancer diagnosis.
Document Details
- Document Type
- Technical Report
- Publication Date
- Nov 01, 2013
- Accession Number
- ADA594312
Entities
People
- Rebekah Drezek
Organizations
- Rice University