Core Modular Blood and Brain Biomarkers in Social Defeat Mouse Model for Post Traumatic Stress Disorder

Abstract

Post-traumatic stress disorder (PTSD) is a severe anxiety disorder that affects a substantial portion of combat veterans and poses serious consequences to long-term health. Consequently, the identification of diagnostic and prognostic blood biomarkers for PTSD is of great interest. Previously, we assessed genome-wide gene expression of seven brain regions and whole blood in a social defeat mouse model subjected to various stress conditions.

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Document Details

Document Type
Technical Report
Publication Date
Aug 20, 2013
Accession Number
ADA596945

Entities

People

  • Bernie J. Daigle Jr.
  • Francis J. Doyle III
  • Linda Petzold
  • Marti Jett
  • Rasha Hammamieh
  • Ruoting Yang
  • Seid Y. Muhie

Organizations

  • University of California, Santa Barbara

Tags

DTIC Thesaurus Topics

  • Alzheimer Disease
  • Anxiety Disorders
  • Blood
  • Blood-Brain Barrier
  • Brain
  • Brain Injuries
  • Cell Physiological Processes
  • Cells
  • Computational Biology
  • Computer Programs
  • Diseases And Disorders
  • Engineering
  • Gene Expression
  • Health Services
  • Protein-Protein Interactions
  • Systems Biology
  • Traumatic Stress Disorder

Fields of Study

  • Psychology

Readers

  • Immunology and Pathology
  • Mental Health of Military Veterans with Posttraumatic Stress Disorder (PTSD): Risk Factors, Prevalence, Symptoms, and Treatment.
  • Political Violence and Terrorism Studies.