Closed Loop Fluid Delivery System

Abstract

Trauma, hemorrhage and burns leads to hypovolemia and hypovolemic shock. Fluid therapy restores normalcy in physiological endpoints, such as cardiac output and blood pressure, but can result in secondary insults, such as excessive edema, if not titrated well. Fluid therapy is labor intensive and requires significant attention by caregivers, who can be overwhelmed in a mass casualty situation. Closed loop fluid resuscitation systems hold great potential to optimize fluid therapy with fewer secondary insults, respond more quickly to changes in patient condition, automate caregiver tasks, reduce variability in care due to fatigue or inexperience and be a force multiplier in mass casualty situations. In this project we have iteratively developed a closed loop fluid delivery system (CLFDS) and conducted a human hemorrhage model clinical study. Clinical data indicates the CLFDS maintains target blood pressure with less fluid and extravascular fluid than the standard of care approach.

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Document Details

Document Type
Technical Report
Publication Date
Feb 28, 2014
Accession Number
ADA597495

Entities

People

  • Christopher L. Meador

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Anesthesia
  • Blood
  • Blood Flow
  • Cardiovascular Physiological Phenomena
  • Computers
  • Drug Therapy
  • Graphical User Interface
  • Health Services
  • Heart Rate
  • Hemorrhage
  • Hypovolemia
  • Medical Personnel
  • Patient Care
  • Standards
  • Tablet Computers
  • Therapy
  • User Interface

Fields of Study

  • Medicine

Readers

  • Cardiovascular Physiology
  • Control Systems Engineering.
  • Trauma or Military Medicine