Mission Connect Mild TBI Translational Research Consortium

Abstract

The purpose of this project is to identify the incidence of post traumatic hypopituitarism (PTH) in mild TBI and develop criteria for assessing which patients with a mid TBI are at risk for developing PTH. This study will also correlate the characteristics of the individuals with PTH by neorpsychological, neurophysiological and imaging testing as they relate to functional outcome. At 6 months post injury, patients will be screened for anterior pituitary function of the 56 mTBI subjects with IGF-1 results, of the 63 who completed the 6 month visit, the results fell below the lower threshold for 14% when using the Quest Diagnostics reference values. However, when the TBI was used, there were 31 subjects (55%) that met the criteria for hypopituitarism, with this finding, similar to that found in moderate-severe TBI population.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2013
Accession Number
ADA599221

Entities

People

  • Brent E. Masel

Organizations

  • Transitional Learning Center

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • Blast Injuries
  • Brain Injuries
  • Consortiums
  • Deficiencies
  • Department Of Defense
  • Dysfunction
  • Health Services
  • Hormones
  • Information Operations
  • Medical Personnel
  • New York
  • Pituitary Hormones
  • Standards
  • Testosterone
  • United States

Fields of Study

  • Medicine

Readers

  • Clinical Trial Research.
  • Neuroscience
  • Systems Analysis and Design