Preventing Vision Loss from Blast Injuries with Regenerative Biomaterial
Abstract
Seryx Biomedical, Inc., in collaboration with the Weill Cornell Medical College is developing a novel regenerative biomaterial derived from the silk protein fibroin from the Bombyx mori silkworm. This will be the first ophthalmic product that utilizes regenerative silk protein for use on the ocular surface. Over 6 million Americans sustain traumatic injuries each year from both accidents and surgical procedures. In addition, eye injury is the number one cause of field evacuation in the military. Corneal wounds cause intense pain and may lead to blindness depending on the severity of injury. Seryx s regenerative biomaterial accelerates corneal healing and soothes the damaged surface by providing a coating over the injury site. In addition, work from this award has demonstrated the protein also possesses anti-inflammatory properties. This regenerative material is a renewable resource, inexpensive to manufacture, and can be produced utilizing a fully scalable GMP process. As a result silk fibroin protein offers much promise for future biomaterial applications in ophthalmology and also in a broader biomedical context.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 01, 2013
- Accession Number
- ADA600398
Entities
People
- Brian D. Lawrence