Sealing Penetrating Eye Injuries Using Photo-activated Bonding
Abstract
To develop a light-activated technology (called PTB) with the potential to decrease vision loss and ocular complications in warfighters sustaining penetrating eye injuries. Scope: To compare light-activated bonding of amnion to direct sealing of penetrating cornea wounds, to evaluate photobonding for puncture wounds in sclera, and to evaluate safety of photobonding to the iris. Major findings: Identified the treatment parameters for rapidly and strongly sealing amniotic membrane over scleral puncture wounds. Demonstrated that photobonding amion effectively sealed wounds for simple and complex corneal lacerations. Determined that sealing penetrating cornea wounds using a dye-stained amniotic membrane patch and green light is superior to direct photo-activated bonding of the woundwalls. Established that the green light parameters used to seal amnion over cornea wounds are below the threshold for thermal damage to the iris. Pathological Evaluation pending at the time of this report.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 01, 2013
- Accession Number
- ADA600570
Entities
People
- Anthony Johnson
- Sheri Demartelaere
Organizations
- Henry M. Jackson Foundation for the Advancement of Military Medicine