Intravesical NGF Antisense Therapy using Lipid Nanoparticle for Interstitial Cystitis
Abstract
The Technology Therapeutic Development Award titled Intravesical NGF antisense therapy using lipid nano-particle for interstitial cystitis evaluates the feasibility of an anti-nerve growth factor (NGF) bladder drug delivery system targeting Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS), IC/PBS is a chronic, severely debilitating disease of the urinary bladder. The goal of this project is to advance key preclinical experiments towards the development of a new drug. Specific aims include experiments, manufacture, and animal testing of experimentsal formulations. During the first year of the project, progress has been made according to the statement of work. Advancements in the development of product formulation and completion of initial manufacturing runs were accomplished. Progress on the timeline towards study drug investigation in advanced diseased animal models is on schedule.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2013
- Accession Number
- ADA600794
Entities
People
- Michael B Chancellor