Development of a Dedicated Radiotherapy Unit with Real-Time Image Guidance and Motion Management for Accelerated Partial Breast Irradiation
Abstract
The purpose of this study is to develop a dedicated image-guided external-beam radiotherapy system for accelerated partial breast irradiation (APBI). We have made significant progress in the past year for this grant focusing on building each sub-system of the proposed apparatus - Aim 1 for the x-ray generator, Aim 2 for the imaging sub system and Aim 3 for the treatment planning. For Aim 1 we are concentrating on analyzing the shielding cost and imaging quality for different energies using Monte Carlo simulations. These results are critical to our final decision on the x-ray source. The panoramic CBCT technology is the heart of the imaging sub system as it reduces the hardware and construction cost. To these ends, we have spent a significant amount of resources on image stitching algorithms and developed parallel processing schemes using GPU for speeding up CBCT reconstructions. Treatment planning is also critical to a successful radiotherapy system. Because the design of the proposed APBI machine is different from conventional linear accelerator, a new treatment planning system (TPS) is being built using the Clarkson and pencil beam convolution methods. An inverse planning algorithm has also been developed using a generic algorithm that takes advantages of the novel irradiation geometries of the proposed ABPI apparatus.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 01, 2012
- Accession Number
- ADA601791
Entities
People
- K. S. Chao