Information Processing and Collective Behavior in a Model Neuronal System

Abstract

This project used neurons in the suprachiasmatic nucleus to understand information processing and collective behavior. The work is computational, and all work done with mathematical models that have been fit to experimental data. Models simulated up to 20,000 neurons in which internal molecular oscillations, with a period of around a day, are generated. On a fast neuronal timescale, these rhythms are co-ordinated and used to process environmental information. By studying this system, we learn about how multiagent systems can efficiently process environmental signals. Our progress was superb and lead to many key papers in high-impact journals. There was also great interest in our work, and we were called on to additionally explore how similar systems in other tissues (e.g. the heart) or organisms (e.g. the Monarch, which is currently being studied by other AFOSR researchers). This was done in addition to meeting the original goals of the grant.

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Document Details

Document Type
Technical Report
Publication Date
Mar 28, 2014
Accession Number
ADA601965

Entities

People

  • Daniel B. Forger

Organizations

  • University of Michigan

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Air Force
  • Air Force Research Laboratories
  • Applied Mathematics
  • Biological Rhythms
  • Biology
  • Brain
  • Circadian Rhythms
  • Computational Biology
  • Computational Science
  • Electrophysiology
  • Experimental Data
  • Health Services
  • Information Processing
  • Mathematical Analysis
  • Mathematical Models
  • Medical Personnel
  • Simulations

Readers

  • Distributed Systems and Data Platform Development
  • Molecular and Cellular Biology
  • Team-Based Human-Centered Cognitive Task Decision Making and Information Performance.