Protein, Lipid, Chemical and Structural Signatures of Differentially-Cultivated Francisella tularensis and Acinetobactor baumannii

Abstract

The goal of this project is to identify bacterial protein and/or lipid markers of cultivation history. In the long run, such information could be used to determine weather a bacterium was previously cultivated in the laboratory or grown in the bacterium's natural environment. In furtherence of this goal, we are building protein- and lipid-composition databases (comprised of three biological replicates) of Francisella tularensis (Ft) and Acinetobactor baumannii (Ab) grown under four representative standard lab conditions (SLCs) and three of the bacterium's native environmental conditions (NEC). We are also sequencing the genome of our Ab to facilitate proteomic analysis of this strain.

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Document Details

Document Type
Technical Report
Publication Date
Mar 05, 2014
Accession Number
ADA602482

Entities

People

  • Karsten Kazlet

Organizations

  • Albany Medical College

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Agreements
  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Bacterial Proteins
  • Chemistry
  • Chemotherapy
  • Department Of Defense
  • Engineering
  • Environment
  • Gammaproteobacteria
  • Lipids
  • Mathematics
  • Proteins
  • Proteomics
  • Standards
  • Two Dimensional

Fields of Study

  • Biology
  • Environmental science

Readers

  • Facility/Structural Engineering.
  • Immunology
  • Molecular and genetic basis of cancer.

Technology Areas

  • Biotechnology