Can Post mTBI Neurological Soft Signs Predict Postconcussive and PTSD Symptoms: A Pilot Study
Abstract
Neurological soft signs (NSS) are subtle indicators of brain dysfunction. NSS have been found to be elevated in a variety of mental disorders, including post-traumatic stress disorder (PTSD), but they have scarcely been studied in TBI. The present study in progress is measuring NSS in the acute aftermath of a mTBI and evaluating their ability to predict subsequent postconcussive symptoms. To date we have screened 55 subjects via the Massachusetts General Hospital Emergency Department leading to 10 viable subjects that have been enrolled, one of whom was subsequently excluded after a positive urine screen. Six of 9 enrolled subjects have successfully completed the full three-month protocol. Their videorecorded data has been encrypted and is awaiting analysis by our off site consultant, Dr. Gurvits, the originator of the NSS battery in current use. We are actively screening subjects at the Emergency Department at the approximate rate of 3 per two weeks and are optimistic about reaching our target enrollment of 20-24 subject in the next 4 months. No preliminary data analyses have been performed.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 2012
- Accession Number
- ADA602679
Entities
People
- Roger K. Pitman
Organizations
- Massachusetts General Hospital