Microbial Degradation of RDX and HMX

Abstract

The present SERDP funded project (CU1213) responds directly to the original SERDP statement of need (CUSON-01-05) to address the cleanup of the two powerful and widely used explosives hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) and octahydro-1,3,5,7- tetranitro-1,3,5,7-tetrazocine (HMX). Both of these cyclic nitramine explosives are used extensively by the military and they are released to the environment during manufacturing, testing and training, demilitarization and open burning/open detonation (OB/OD). Such activities lead to the contamination of surface and subsurface soil. Also, because of their solubility (50 mg/L and 5 mg/L for RDX and HMX at 25 C, respectively) in water and their weak binding affinity for soil, both RDX and HMX migrate through subsurface soil and cause groundwater contamination. One of the most recent examples is the well-publicized contamination of the aquifer at the Massachusetts Military Reservation on Cape Cod. Cyclic nitramine explosives are toxic to aquatic organisms (Sunahara et al., 1999; Talmage et al., 1999), earthworms (Robidoux et al., 2000, 2001), mammals (Talmage et al., 1999) and human monocytes (Bruns-Nagel et al., 1999), and above all, they are also carcinogenic. The toxicity of cyclic nitramines necessitates that contaminated soil and groundwater be remediated using cost effective and environmentally safe processes such as bioremediation. Incineration is not a desirable remediation option because of high costs and hazardous emissions. Several studies reported biodegradation of RDX and HMX under both anaerobic and aerobic conditions using anaerobic sludge (McCormick et al., 1981), consortia (Funk et al., 1993), or specific isolates (Kitts et al., 1994; Binks et al., 1995; Young et al., 1997a; Coleman et al., 1998; and Boopathy et al., 1998). Despite these early efforts, there is little existing information regarding ring cleavage products and the enzymes that lead to their formation.

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Document Details

Document Type
Technical Report
Publication Date
Feb 01, 2004
Accession Number
ADA604122

Entities

People

  • Annamaria Halasz
  • Bharat Bhushan
  • Carl Groom
  • Diane Fournier
  • Jalal Hawari
  • Jian-shen Zhao
  • Jim C. Spain
  • Louise Paquet
  • Tara Hooper
  • Vimal Balakrishnan

Organizations

  • Air Force Research Laboratory

Tags

Communities of Interest

  • Biomedical
  • Weapons Technologies

DTIC Thesaurus Topics

  • Biodegradation
  • Chemical Reaction Properties
  • Chemical Synthesis
  • Chemistry
  • Fungi
  • Liquid Chromatography
  • Mass Spectrometry
  • Microbiology
  • Organic Chemistry

Fields of Study

  • Environmental science

Readers

  • Agricultural Chemistry/Soil Science
  • Medical Imaging.

Technology Areas

  • Biotechnology
  • Biotechnology - Bioremediation