Vision Integrating Strategies in Ophthalmology and Neurochemistry (VISION)
Abstract
The overall goals of the VISION project are to identify new neuroprotective agents in mouse models of injury to the visual axis and propose therapeutic candidates for preserving vision in warfighters who have sustained ocular injuries. In our first year of this project, we have recruited and hired knowledgeable and dedicated scientists to establish the infrastructure necessary for the proposed studies. During this first year, we established: (1) animal model and histology core laboratories, (2) a sophisticated data management system, (3) all 3 models of injury to the visual axis, (4) techniques for the quantitative assessment of injury-induced damage to visual axis tissues, and (5) in vitro assessment of 4 novel neuroprotective agents. We are now ready to test these neuroprotective agents in our models and will identify additional neuroprotective pathways in Year 2 of this project.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 01, 2011
- Accession Number
- ADA606303
Entities
People
- Thomas Yorio
Organizations
- University of North Texas Health Science Center