In Vitro Osteoblast Model for Bone Wound Infections and Antimicrobial Therapy

Abstract

The developmental processes for bone tissue is complex and involves several tightly regulated gene expression patterns of bone associated proteins. The expression of these genes and proteins are regulated in a temporal manner both in vivo and in vitro and has previously been studied in both these systems. The process of osteoblast differentiation can be subdivided into 3 stages, namely, proliferation, extracellular matrix synthesis and maturation and, lastly, mineralization.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2013
Accession Number
ADA608594

Entities

People

  • Chrysanthi Paranavitana

Organizations

  • Geneva Foundation

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Anti-Infective Agents
  • Bacteria
  • Biomedical Research
  • Cells
  • Department Of Defense
  • Electronic Mail
  • Infection
  • Information Operations
  • Instructions
  • Osteoblasts
  • Wound Infections
  • Wounds And Injuries

Fields of Study

  • Biology

Readers

  • Immunology and Pathology
  • Molecular Genetics