Bioactive Coating Systems for Protection Against Bio-Threats: Antimicrobial Coatings for Medical Shelters

Abstract

Over the course of this program, the Center for Nanoscale Science and Engineering (CNSE) at North Dakota State University (NDSU) in partnership with Triton Systems, Inc. augmented its core materials science research capabilities to foster the development of next generation, antimicrobial coating technologies aimed at protecting US military personnel from exposure to hazardous biological agents in the battlefield. A key element to the success of this project was the development, early on, of a high-throughput biological screening workflow to enable combinatorial exploration of novel antimicrobial coating/treatment concepts. A number of different strategies based on reactive, functional oligomers containing quaternary ammonium salts (QAS) were investigated for their ability to impart antimicrobial properties to both fabrics (i.e., nylon and polyester) and other rigid materials (i.e., glass and metals) of relevance to the US military. One approach in particular, based on QAS-functional acrylates, was shown to be highly effective at generating broad-spectrum, antimicrobial treatments for polyester fabric using Triton Systems novel atmospheric pressure plasma deposition process (Invexus ). It is envisioned that these new antimicrobial technologies developed at NDSU will be harnessed by Triton Systems to produce efficacious and operationally functional products for the US military via their industrial scale, textile treatment line (RC1000 ).

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Document Details

Document Type
Technical Report
Publication Date
Dec 23, 2013
Accession Number
ADA608969

Entities

People

  • Apoorva Shah
  • Arjan Giaya
  • Bret Chisholm
  • James Bahr
  • Satyabrata Samanta
  • Shane Stafslien
  • Yoojeong Kim

Organizations

  • North Dakota State University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Alkenes
  • Anti-Infective Agents
  • Bacteria
  • Barometric Pressure
  • Cellular Structures
  • Chemical Synthesis
  • Chemistry
  • Engineering
  • Materials
  • Materials Science
  • Materials Testing
  • Microbiology
  • North Dakota
  • Staphylococcus Aureus
  • Students
  • Swatches
  • Test Methods

Readers

  • Critical Infrastructure Protection in CBRN and WMD Threats.
  • Military/Explosive Ordnance Disposal (EOD) Technology
  • Molecular and Cellular Biochemistry