Synthesis of C13- and N15-Labeled DNAN
Abstract
Isotopically labeled (C13 and N15) and unlabeled DNAN were synthesized in two steps from chlorobenzene in high purity and regioselectivity with an overall yield of 69% from readily available materials. The syntheses and full characterizations (H1, C13, N14, N15 NMR, IR, and HRMS) of labeled and unlabeled DNAN, as well as its synthetic precursor, 1-chloro-2,4-dinitrobenzene, are discussed. The use of isotopically labeled material and their spectra will enable the toxicity and biodegradation potential of DNAN to be more easily determined.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 24, 2014
- Accession Number
- ADA609833
Entities
People
- Joseph D. Mannion
Organizations
- Naval Surface Warfare Center Indian Head Division