Field Evaluations of Topical Arthropod Repellents in North, Central, and South America

Abstract

Recently, vector-borne diseases have been resurging in endemic areas and expanding their geographic range into nonendemic areas. Such changes have refocused attention to the potential for major public health events, as native populations are exposed to these pathogens. Personal topical repellents, recommended by the United States Centers for Disease Control and Prevention and World Health Organization, remain a first line of protection against infection. The current study evaluated the repellent efficacy of four new U.S. Environmental Protection Agency-registered topical repellent products, two with picaridin as the active ingredient and two with IR3535, against a standard DEET (N,N-diethyl-3-methylbenzamide) based product. All products were evaluated against a wide range of vector species under field conditions across the Americas. Human volunteers were used to evaluate product efficacy as compared with a well-known DEET-based formulation and determine suitability for use by the U.S. military. Findings demonstrated the new formulations performed as well as the standard U.S. military repellent and could be recommended for use.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2014
Accession Number
ADA610105

Entities

People

  • John P. Benante
  • Kendra L. Lawrence
  • Kirk D. Mundal
  • Nicole L Achee
  • Ulrich R. Bernier

Organizations

  • Walter Reed Army Institute of Research

Tags

DTIC Thesaurus Topics

  • Arthropod Borne Diseases
  • Biomedical Research
  • Climate Change
  • Dengue
  • Disease Outbreaks
  • Environmental Protection
  • Equine Encephalitis
  • Geography
  • Infectious Diseases
  • Institutional Review Board
  • Malaria
  • Medical Personnel
  • North America
  • Public Health
  • Ticks
  • United States
  • Viruses

Readers

  • Infectious Disease/Epidemiology
  • Systems Analysis and Design
  • Vector-Borne Disease and Entomology