Advanced Sensors for TBI

Abstract

The purpose of this project is to create new sensor technologies and perform preliminary studies in an impact model of TBI for subsequent rapid transition to testing in blast TBI models with future funding opportunities. The hypothesis is that measurement of intracranial pressure transients in an impact model of traumatic brain injury will provide valuable data about sensor performance within a biological system that will be directly applicable to subsequent transition into blast TBI animal models. Scope: Miniaturized, state-of-the-art pressure/temperature sensors will be engineered and fabricated to measure the immediate increases in intracranial pressure (ICP) combined with longer-term measurements of biological ICP and intracranial temperature during experimental TBI. Experiments will measure of acute transmission of pressure waves through the brain, longer-term changes in biological ICP, and intracranial temperature. Major Findings: Currently, the first lot of pre-etched silicon-on-insulator wafers have been built. Those wafers are now entering processing to define the ion implants and metal contacts to create the strain-sensitive circuit of the device. We are performing failure testing of the diced and etched wafers on in a custom designed bending apparatus

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2014
Accession Number
ADA610836

Entities

People

  • Bruce Lyeth

Organizations

  • University of California

Tags

Communities of Interest

  • Advanced Electronics
  • Biomedical
  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Accuracy
  • Biomedical Research
  • Brain Diseases
  • Brain Injuries
  • Central Nervous System Diseases
  • Cerebral Edema
  • Dielectrics
  • Engineering
  • High Pressure
  • High Temperature
  • Measurement
  • Metal Contacts
  • Models
  • Pressure Measurement
  • Substrates
  • Systems Biology
  • Transitions

Readers

  • Neurotrauma and Rehabilitation Medicine.
  • Optical Fiber Sensing and Electromagnetic Propagation.
  • Semiconductor Device Technology

Technology Areas

  • Microelectronics
  • Microelectronics - Microelectromechanical Systems