Objective Methods to Test Visual Dysfunction in the Presence of Cognitive Impairment

Abstract

Purpose: to develop and validate objective tests to diagnose vision deficits in patients with cognitive impairment and ensure effective monitoring of treatment. Scope: objective methods to monitor vision include 1) the pupil light reflex, 2) light evoked potentials from the brain and from the eye and 3) purposeful eye movements to track moving targets that are resolved. Major Findings (year two): 1) a prototype, dry electrode system was delivered in Year 2 and was evaluated with specified requirements met, 2) a Smart Eye head and ocular tracking system was further tested and optimized in conjunction with a high contrast, high luminance 55 monitor for presenting visual stimuli for eye movement, pupil responses and cortical visual evoked potentials (VEPs), 3) a software architecture (matrix approach) for regional visual field stimulus presentation, data synchronization, and analysis from visual cortical responses recorded from scalp electrodes was developed and completed. Significance: objective tests of vision based on eye tracking of visual targets, pupil responses, and cortical visual evoked potentials will greatly improve eye care by providing faster, lower cost testing that can be performed in remote settings and will provide a new tool for assessing innovative treatments being developed to save or restore vision.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2012
Accession Number
ADA610976

Entities

People

  • Pieter Poolman
  • Randy H. Kardon

Organizations

  • University of Iowa

Tags

DTIC Thesaurus Topics

  • Brain Injuries
  • Cognitive Impairment
  • Contrast
  • Diseases And Disorders
  • Dysfunction
  • Electrodes
  • Electrophysiological Phenomena
  • Eye
  • Eye Movements
  • Graphical User Interface
  • Head (Anatomy)
  • Medical Personnel
  • Moving Targets
  • Neural Pathways
  • Targets
  • Test Methods
  • Waveforms

Fields of Study

  • Medicine

Readers

  • Vision Science/Vision Psychology/Cognitive Neuroscience.