Hyperbaric Oxygen Therapy in the Treatment of Chronic Mild-Moderate Blast-Induced Traumatic Brain Injury PCS and PTSD

Abstract

The purpose of the study is to see if an eight-week course of forty low-pressure HBOT s can significantly improve symptoms and cognitive function in military veterans and civilians with mild TBI/PPCS. The proposed design is a randomized controlled (non-treatment, non-sham) single-arm crossover single-blind study. The scope of the project is to recruit, enroll, test, treat, re-test and follow-up on 50 subjects at Louisiana State University, New Orleans in 23 months and another 50 subjects at Oklahoma State University in an equivalent period of time. The study received final approval from all regulatory agencies on 5/13/2014. Enrollment began shortly thereafter. Thus far seven subjects have been enrolled. One enrolled subject defaulted on treatment due to urgent personal commitments at the time of enrollment. The other six are proceeding through the protocol. Three additional subjects have passed nearly all screening measures and will be undergoing the final screening and enrollment in the next 3 weeks. There are no study results to report at this time and no significant adverse advents.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2014
Accession Number
ADA611613

Entities

People

  • Paul G. Harch

Organizations

  • Louisiana State University

Tags

DTIC Thesaurus Topics

  • Anxiety Disorders
  • Biomedical Research
  • Brain Injuries
  • Health Services
  • Louisiana
  • Medical Personnel
  • Oklahoma
  • Recruits
  • Therapy
  • Traumatic Stress Disorder
  • United States
  • Universities

Readers

  • Psychological Intervention/Treatment for Stress, Anxiety, PTSD, and Related Emotional and Cognitive Health Symptoms.
  • Technical Research and Report Writing.