Glyco-Immune Diagnostic Signatures and Therapeutic Targets of Mesothelioma

Abstract

The focus of this grant is to investigate immunoprofiles for serum antibodies to aberrant glycans in human and animal models of mesothelioma. This is accomplished using a one of a kind printed glycan array which is at NYU School of Medicine (NYUSoM). It is hoped that these experiments will allow us to diagnose and prognosticate mesothelioma more accurately in the future. We have been severely limited by our ability to start the human mesothelioma glycoprofiles as well as the animal profiles due to delivery and set up times for our one of a kind glycomics laboratory at NYUSoM. We summarize the situation in the progress report with the good news that we will be moving onwards in June with these studies.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2014
Accession Number
ADA612709

Entities

People

  • Margaret Huflejt

Organizations

  • New York University

Tags

DTIC Thesaurus Topics

  • Antibodies
  • Biomedical Research
  • Blood
  • Breast Cancer
  • Cancer
  • Carcinogens
  • Cell Line
  • Cells
  • Chemistry
  • Diseases And Disorders
  • Human Population
  • Immune System
  • Laboratory Animals
  • Medical Personnel
  • Mesothelioma
  • Neoplasms
  • New York

Fields of Study

  • Biology

Readers

  • Military Engineering.
  • Systems Analysis and Design
  • Technical Research and Report Writing.