Microvesicle Production after Trauma and Its Clinical Impact on Venothromboembolism

Abstract

Polytrauma is most often casused from explosive devices and accounts for about 65 percent of injuries to our military personnel. The patients who have polytrauma are at increased risk of developing either bleeding and/or a clot in their veins which cause a life-threatening event known as venous thromboembolism (VTE). We began enrollment of patients into the study on 2 February 2011. As of 1 October 2013, we have thus far analyzed plasma samples of over 426 patients and volunteers. In our preliminary analysis of thrombin generation and procagulant microvesicles noted after traumatic injury relative to healthy volunteers.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2013
Accession Number
ADA612872

Entities

People

  • Myung S. Park

Organizations

  • Mayo Clinic

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Anticoagulants
  • Biomedical Research
  • Blood
  • Blood Coagulation Factors
  • Data Analysis
  • Demographic Cohorts
  • Department Of Defense
  • Embolism And Thrombosis
  • Explosive Devices
  • Health Services
  • Medical Personnel
  • Microparticles
  • Military Personnel
  • Production
  • Statistical Analysis
  • Volunteers

Fields of Study

  • Medicine

Readers

  • Aviation Safety Risk Assessment.
  • Clinical Trial Research.
  • Trauma Surgery or Emergency Medicine.