A Randomized, Controlled Trial of Meditation Compared to Exposure Therapy and Education Control on PTSD in Veterans

Abstract

This single-blinded, RCT will: 1) evaluate effects of Transcendental Meditation (TM) vs. Prolonged Exposure (PE) and PTSD health education control (EC), using the Clinician Administered PTSD Scale (CAPS) (primary outcome); 2) evaluate effects of TM vs. controls on PTSD symptoms (PCL-M), depressive symptoms and other psychological distress measures, quality of life, and physiological/biochemical stress markers; and 3) evaluate treatment compliance. The study will enroll 210 subjects (70 per group). The VA San Diego is the field site with testing conducted at 0 and 3 months The research will provide data on the feasibility and efficacy of TM as an alternative therapy for PTSD. Our collaborative group (Maharishi University of Management Research Institute, VA San Diego Healthcare System, University of California at San Diego) has made excellent progress in year one. Since securing IRB and DoD human subjects approvals the end of May 2012, we completed hiring all staff, finalized procedures for conducting the study, are currently on target for randomization, with 95 subjects randomized to date (target of 93) and have good treatment compliance, with over 70% treatment sessions attended. Post-testing compliance is greater than 80%.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2014
Accession Number
ADA613059

Entities

People

  • Sanford Nidich
  • Thomas Rutledge

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • California
  • Data Analysis
  • Delivery Of Health Care
  • Department Of Defense
  • Department Of Veterans Affairs
  • Education
  • Electronic Mail
  • Employment
  • Genetic Markers
  • Genetic Testing
  • Health
  • Institutional Review Board
  • Personnel Management
  • Quality Control
  • Quality Of Life
  • Universities

Readers

  • Allergy and Immunology.
  • Mental Health of Military Veterans with Posttraumatic Stress Disorder (PTSD): Risk Factors, Prevalence, Symptoms, and Treatment.
  • Psychological Intervention/Treatment for Stress, Anxiety, PTSD, and Related Emotional and Cognitive Health Symptoms.