Biological and Genomic Differences of ERG Oncoprotein-Stratified Prostate Cancers from African and Caucasian Americans
Abstract
There is striking disparity in prostate cancer (CaP) incidence and mortality for African-American (AA) men as compared to Caucasian Americans (CA). Biological basis for this disparity has not been established. Oncogenic activation of ERG resulting from prevalent gene fusions is present in two thirds of CaP patients in Western countries.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2014
- Accession Number
- ADA613185
Entities
People
- Gyorgy Petrovics
Organizations
- Henry M. Jackson Foundation for the Advancement of Military Medicine