Absorbable Antimicrobial Battlefield Hemostat
Abstract
Uncontrolled bleeding on the battlefield results in a 90% mortality rate within the first hour. Unfortunately, in combat operations, such medical intervention within the golden hour is not always possible, and 50% of battlefield deaths are still due to traumatic hemorrhage. The injury and continued bleeding of the compromised patient needs novel hemostats. A potential solution to this problem is an effective battlefield hemostat that can be resorbed by the body without the requirement for device removal. The object of this proposal is to develop nanomaterial hemostat based on silica nanofibers. Nanosys Inc. and University of North Dakota (UND) have built some platforms to move to the next step by improving the antimicrobial efficacy of the dressing and subsequently, improving its resorptive properties ensuring that this dressing becomes a complete solution for DoD. Our research results suggest that the nanofibers can be resorbed but we would likely need to limit the amount of material left in for effective resorption. The silicon nanofibers did not cause any major irritation, toxicity, and/or inflammatory response, and may represent new formats of hemostat materials that can quickly and effectively stop bleeding at the battlefield.
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 01, 2013
- Accession Number
- ADA613227
Entities
People
- Julia Zhao
Organizations
- University of North Dakota