Treatment of Early Post-Op Wound Infection after Internal Fixation
Abstract
Postoperative infection is one of the most prevalent and challenging complications faced by orthopaedic surgeons and patients in both the military and civilian populations. The wounds are contaminated or colonized at the time of injury, during the course of therapy, or both. Infection is always a possibility with any surgical intervention, particularly in the setting of orthopaedic trauma where multiple factors make the prevention and treatment of these infections very complicated. Due to the difficulties we have had with randomization, we felt that it was critical to establish the external validity of the results in an observational cohort. The observational amendment was approved by the Johns Hopkins School of Public Health IRB on July 9, 2014 and we received acknowledgment of this amendment from the DoD on September 18, 2014. The sites are in the process of obtaining approval of the observational amendment locally. We have initiated training calls between the study PI, coordinating center and individual sites. The purpose of these calls is to assist the sites which issues regarding recruitment, enrollment and study conduct. During the past year we received feedback from the sites that some physicians were having difficulty maintaining equipoise when prescribing antibiotics. Informational slides have been developed for the sites to use to present the study to their Infectious Disease teams to assist with this problem.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2014
- Accession Number
- ADA613441
Entities
People
- William Obremskey
Organizations
- Vanderbilt University