Plutonium 238/239 Decorporation Model
Abstract
A treatment model for Pu-238/239 internal contamination by DTPA was developed to evaluate efficacy of various treatment regimens. The model estimates Pu deposition, absorption, distribution, retention, excretion, and response to DTPA after an inhalation exposure. It estimates the acute red bone marrow and lung doses and whole body effective dose as a function of time. Model results compare favorably with human and animal data. Outputs from the model include Pu deposition in the respiratory tract, distribution in tissue compartments over time with and without treatment, excretion rates, and radiation doses to critical organs. Calculations from the model may be used to analyze consequences of exposure to Pu and the effect of treatment.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2014
- Accession Number
- ADA613578
Entities
People
- Daniela Strickling
- Gene E. Mcclellan
- Jason Radriguez
- Kyle K. Millage
Organizations
- Applied Research Associates (United States)