Vapor Pressure Determination of VM Using the Denunder-Liquid Chromatography-Mass Spectrometry Technique
Abstract
The vapor pressure of O-ethyl S-2-(diethylamino) ethyl methylphosphonothiolate (VM) has been determined using a novel, denuder-based liquid chromatography mass spectrometry (LC MS) approach designed specifically for low volatility and thermally unstable materials. This system incorporates a novel, packed-bed, vapor-generation system specifically designed to deliver low-volatility and thermally unstable compounds at low or high flow rates using milligram quantities of the material. The vapor pressure analysis system takes advantage of denuder technology to efficiently transfer the chemical sampled from the airstream into a liquid vehicle for transport to a detector such as LC MS. Capturing the chemical of interest into a liquid vehicle eliminates the need for heated transfer lines by virtually eliminating line losses. The results of the vapor pressure study of VM are presented.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 2015
- Accession Number
- ADA613614
Entities
People
- Ai Sohrabi
- Amanda L. Jenkins
- Eric J. Bruni
- Leonard C. Buettner
- Michael W. Ellzy
Organizations
- Edgewood Chemical Biological Center