Optimization of Soft Tissue Management, Spacer Design, and Grafting Strategies For Large Segmental Bone Defects Using The Chronic Caprine Tibial Defect Model

Abstract

This proposal addresses the treatment of segmental bone defects and methods that can be used to manipulate the Masquelet induced membrane (IM) to create a graft bed that optimizes bone regeneration. The Chronic Caprine Tibial Defect (CCTD) model is used 1) to improve surgical technique and 2) to optimize spacer design; these are likely to advance bone regeneration strategies and translate into clinical practice

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2014
Accession Number
ADA613641

Entities

People

  • Jonathan A. Forsberg

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Blood Coagulation
  • Bone And Bones
  • Bone Regeneration
  • Cartilage
  • Cells
  • Chemistry
  • Connective Tissue
  • Gene Expression
  • Growth Factors
  • Materials
  • Membranes
  • Military Medicine
  • Osteogenesis
  • Peptide Growth Factors
  • Proteins
  • Stem Cells
  • Tissues

Fields of Study

  • Medicine

Readers

  • Immunology and Pathology
  • Nanocomposite Materials Science
  • Oncology