Refining an Automated Transcranial Doppler System for the Detection of Vasospasm after Traumatic Brain Injury

Abstract

Traumatic brain injury (TBI) is a major contributor to morbidity and mortality experienced by those soldiers subjected to improvised explosive devices (IED) as well as in military and civilian high speed collisions. Traumatic cerebral vasospasm (TCV) is a major contributor to morbidity and mortality experienced by those TBI patients. Aggressive neurosurgical treatment motivated by early diagnosis appears to improve the clinical outcome for these patients. Early transcranial Doppler (TCD) measurements of blood flow speed within major cerebral arteries produces the initial diagnosis, hence motivates the rapid treatment of TCV. However, the skill necessary to deploy TCD limits its availability relative to its need. PhysioSonics, Inc, a local company in Seattle, created an automatic TCD system (called Presto or aTCD) that minimizes the skill necessary to perform TCD assays. Our long-term goal is to optimize Presto for patients in vasospasm, through optimization of its spectral Doppler envelope analyzer, its headset and supporting software so it can track blood flow in the internal carotid artery as well as middle cerebral artery.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2014
Accession Number
ADA613647

Entities

People

  • Pierre D. Mourad

Organizations

  • University of Washington

Tags

Communities of Interest

  • Biomedical
  • Ground and Sea Platforms
  • Weapons Technologies

DTIC Thesaurus Topics

  • Arteries
  • Biomedical Research
  • Blood
  • Blood Flow
  • Blood Vessels
  • Brain Injuries
  • Cardiovascular Physiological Phenomena
  • Cardiovascular System
  • Doppler Effect
  • Health Services
  • Improvised Explosive Devices
  • Institutional Review Board
  • Measurement
  • Military Medicine
  • Physics Laboratories
  • Statistical Analysis
  • Waveforms

Fields of Study

  • Medicine

Readers

  • Neurotrauma and Rehabilitation Medicine.
  • Oceanography.
  • Trauma Surgery or Emergency Medicine.