MicroRNA in Prostate Cancer Racial Disparities and Aggressiveness

Abstract

Activities during this first year of the project were focused on Tasks 1 and 2 of the statement of work, as planned. Task 1 (months 1-30) is to obtain blood and data for 300 new study subjects. Enrollment opened on March 4, 2014. Between March 4 and September 30, 2014, 44 men were enrolled in the study (Task 1.a), for a total of 553 men towards our goal of 800 men. Of these newly enrolled men, blood was collected on 17 (Task 1.b), for a total of 459 blood samples. Three pre-treatment blood samples were collected (Task 1.c), for a total of 86 towards our goal of 150 pre-treatment samples. Questionnaires were completed by 41 men (Task 1.d), for a total of 529 completed questionnaires. Our enrollment rate among eligible men is~95%. Related to Task 2, we have actively followed all of the enrolled men in the cohort (from the previously funded study and from the current protocol) who did not have extensive disease at diagnosis for PSA outcomes. Mean follow-up time is currently 35 months. Follow-up of PSA test results through medical records and Caisis database have just been updated, and a linkage with Metropolitan Detroit SEER registry (MDCSS) for vital status is underway.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2014
Accession Number
ADA613715

Entities

People

  • Cathryn Bock

Organizations

  • Wayne State University

Tags

DTIC Thesaurus Topics

  • Abstracts
  • African Americans
  • Biogenesis
  • Biological Sciences
  • Biomedical Research
  • Cell Line
  • Databases
  • Department Of Defense
  • Diseases And Disorders
  • Disparities
  • Genes
  • Genetic Variation
  • Neoplasms
  • Prostate
  • Prostate Cancer
  • Questionnaires
  • Regression Analysis

Readers

  • Instructional Design and Training Evaluation.
  • Prostate Cancer Biology.
  • Trauma or Military Medicine