Development and Application of Advanced Ophthalmic Imaging Technology to Enhance Military Ocular Health Capabilities
Abstract
The goal of this research is to advance the frontiers of a promising imaging technology called optical coherence tomography (OCT), developing advanced instrumentation and new software applications to enable high resolution evaluations of the retina and optic nerve that could be easily performed by non-physician health care professionals. The research achieved the following aims: 1) Developed methods for accurate vertical alignment and matching, including the overlay of a color or red-free, fundus photograph on an OCT image for registration; 2) Developed the mathematical algorithms to analyze and quantify OCT datasets automatically including 3D segmentation algorithm for quantitative mapping of the retinal thickness using 3D OCT data for normal and diseased human eyes; 3) Further improved the resolution of the spectral OCT. The developed OCT system has a depth resolution of ~3 m in tissue and is capable of resolving all the sub-retinal features of the retina. The system is also capable of delineate the anatomical structure of the cornea with high imaging quality. The system provides a good diagnostic tool for diseases of both the anterior and posterior segments of the eye.
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 01, 2008
- Accession Number
- ADA613889
Entities
People
- Shuliang Jiao
Organizations
- University of Miami