Prevention of Stimulant-Induced Euphoria with an Opioid Receptor Antagonist

Abstract

The protocol, sponsored by the Department of Defense, is a 6-week study examining whether Methylphenidate-induced euphoria can be attenuated by co-administration with Naltrexone In medication native young adults (age 18-30) with a euphoric response to MPH administered on the Drug Feeling visit. In this double bind study, subjects will receive MPH and Naltrexone or a placebo to treat their ADHD symptoms over the course of the 6-week trial.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2014
Accession Number
ADA613990

Entities

People

  • Thomas Spencer

Organizations

  • Massachusetts General Hospital

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Attention Deficit Disorder
  • Biomedical Research
  • Department Of Defense
  • Electrocardiography
  • Enlisted Personnel
  • Euphoria
  • Families (Human)
  • Food
  • Health Services
  • Insomnia
  • Medical Personnel
  • Military Families
  • Military Personnel
  • Pain
  • Physicians
  • Psychiatry
  • Sleep Deprivation

Fields of Study

  • Psychology

Readers

  • Child and Adolescent Substance Abuse Science in Autism Spectrum Disorders.
  • Circadian Sleep-Wake Regulation and Chronobiology