Multidrug-Resistant Gram-Negative Bacterial and Carbapenem-Resistant Enterobacteriaceae Infections in the Department of the Navy: Annual Report 2013

Abstract

Gram-negative bacterial infections are a growing global public health and clinical concern. Additionally, epidemics of multidrug-resistant (MDR) gram-negative bacteria have occurred worldwide in the last couple decades, including regions where United States (US) military forces are regularly deployed. In 2013, the incidence of MDR Escherichia coli, Enterobacter, Klebsiella, and Pseudomonas aeruginosa in Department of Defense (DOD) beneficiaries seeking care in the Military Health System (MHS) increased from 2012. MDR E. coli was the organism most frequently identified with an incidence 37-40 times higher than the next most frequent organism. A pronounced gender disparity was noted for all organisms except MDR P. aeruginosa. Overall, DOD female beneficiaries were impacted much more than their male counterparts. Furthermore, MDR E. coli, MDR Enterobacter, and MDR Klebsiella cases commonly manifested as urinary tract infections (UTIs), which is consistent with historic observations. In 2013, cases of MDR P. aeruginosa more commonly manifested as respiratory infections, which is also consistent with historic observations. MDR P. aeruginosa did not display any consistent high susceptibilities at the population level.

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Document Details

Document Type
Technical Report
Publication Date
Mar 19, 2015
Accession Number
ADA614086

Entities

People

  • Paul Meddaugh
  • Uzo Chukwuma

Organizations

  • Navy and Marine Corps Public Health Center

Tags

DTIC Thesaurus Topics

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Bacteria
  • Bacterial Infections
  • Gram-Negative Bacteria
  • Gram-Negative Bacterial Infections
  • Health Services
  • Infection
  • Infection Control
  • Medical Personnel
  • Microbiology
  • Military Medicine
  • Pathogenic Bacteria
  • Pharmacies
  • Public Health
  • United States Central Command

Fields of Study

  • Medicine

Readers

  • Economics
  • Microbial Pathology