Predicted Hematologic and Plasma Volume Responses Following Rapid Ascent to Progressive Altitudes
Abstract
Scientific consensus does not exist regarding hematological responses to moderate to high altitude exposure. The purpose of this study was to quantify the expected changes in hemoglobin concentration [Hb], hematocrit (Hct), and PV changes as a result of a given gain in terrestrial elevation, delineate the time course of these changes, and define baseline demographics and physiologic descriptors that are important in predicting these changes. The overall impact of altitude can be summarized using the following correction factors: 1) 0.1g/dl increase in [Hb] for every 500 m increase in altitude regardless of gender, 2) 1.1% increase in Hct at 2000 m with an additional 2-6% increase for every 500 m increase in altitude depending non the altitude, and 3)rapid 5% loss in PV at 2000 m and additional 0.6% decrease with every 500 m above 2000 m. It is anticipated that results will enhance the ability of sport organizations to detect "blood doping" in athletes seeking to gain an edge in their athletic performance.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 2014
- Accession Number
- ADA614246
Entities
People
- Beth A. Beidleman
- Janet E. Staab
- Michael N. Sawka
- Stephen R. Muza
Organizations
- United States Army Research Institute of Environmental Medicine