1029: Tranexamic Acid for Pediatric Trauma

Abstract

Learning Objectives: Tranexamic Acid (TXA) has been shown to decrease mortality in adult trauma. Although TXA has not been reported or studied in pediatric trauma, an increasing number of pediatric centers are employing this medication in massive transfusion (MT) protocols based on adult data. Methods: All pediatric trauma patients recorded in the Department of Defense Trauma Registry from 2006 2013 who received a MT (more than 40ml/kg all blood product) were reviewed. Burn patients and those with fatal head trauma (head AIS 6) were excluded. Patients who received TXA (TXA+) were compared to those who did not (TXA-). Primary outcome was in-hospital mortality and secondary outcomes were 24-hour mortality and blood products transfused.

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Document Details

Document Type
Technical Report
Publication Date
Dec 01, 2014
Accession Number
ADA615871

Entities

People

  • Andrew P Cap
  • Heather Pidcoke
  • Jeremy Cannon
  • Matthew Borgman
  • Philip C Spinella

Organizations

  • United States Army Institute of Surgical Research

Tags

DTIC Thesaurus Topics

  • Blood
  • Brain Injuries
  • Burns
  • Cerebral Edema
  • Gene Expression
  • Health Services
  • Hospitals
  • Intensive Care Units
  • Patient Care
  • Public Health
  • Sepsis
  • Surgery

Fields of Study

  • Medicine

Readers

  • Clinical Trial Research.
  • Trauma or Military Medicine