Self-Assembly of Large-Scale Shape-Controlled DNA Nano-Structures

Abstract

We proposed to develop a methodology by using short synthetic DNA strands to build complex DNA nano-structures. In such a methodology, each short synthetic DNA strand, called DNA brick, is designed as a modular building block to assemble large structure with nanometer scale geometry control. We are using the methodology to build a variety of complex nano-structures, including 1D, 2D, 3D discrete structures and extended crystals. We are also developing a number of real world applications based on these novel structures. The successful development of this modular nano construction methodology and the associated real world applications will have transformative impact.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Dec 16, 2014
Accession Number
ADA616319

Entities

People

  • Peng Yin

Organizations

  • President and Fellows of Harvard College

Tags

Communities of Interest

  • Advanced Electronics

DTIC Thesaurus Topics

  • Chemical Synthesis
  • Chemistry
  • Computer Programs
  • Construction
  • Engineers
  • Fungi
  • Geometry
  • Materials Laboratories
  • Materials Processing
  • Materials Science
  • Materials Testing
  • Metallic Nanoparticles
  • Nanomaterials
  • Nanotechnology
  • Organic Chemistry
  • Surface Plasmon Resonance
  • Synthetic Biology

Readers

  • Computational Fluid Dynamics (CFD)
  • Military History of the United States in the 20th Century.
  • Molecular and Cellular Biochemistry