Analysis of Urinary Metabolites of Nerve and Blister Chemical Warfare Agents

Abstract

This report outlines the instrumental method development for the analysis of human biofluids, in this case urine, for the presence of metabolites of the chemical warfare agents HD, GA, GB, GD, GE, GF, VX and VR using UHPLC MSMS. It also investigates the effect of different sample preparation techniques on the recovery of the analytes, using the analysis method developed.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2014
Accession Number
ADA616381

Entities

People

  • Stuart Thomson

Organizations

  • Defence Science and Technology Group

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Chemical Warfare
  • Chemical Warfare Agents
  • Chemical Weapons
  • Detection
  • Freeze Drying
  • Health Care
  • Health Care Facilities
  • Liquid Chromatography
  • Mass Spectrometers
  • Mass Spectrometry
  • Monitoring
  • Nerve Agents
  • Recovery
  • Spectrometry
  • Standards
  • Warfare

Readers

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  • Analytical Chemistry