IMPACT: Imaging and Molecular Markers for Patients with Lung Cancer: Approaches with Molecular Targets, Complementary/Innovative Treatments, and Therapeutic Modalities

Abstract

The projects in this proposal specifically target several signal transduction pathways known to be critical for NSCLC pathogenesis including the EGFR pathway and the more downstream ras/raf/Mek/ERK pathway. These projects combine targeted approaches using molecular and imaging techniques to validate activity against a target and monitor response using imaging modalities specific to the receptor using either small molecules or targeted peptide approaches.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Feb 01, 2015
Accession Number
ADA617043

Entities

People

  • George Simon

Organizations

  • The University of Texas MD Anderson Cancer Center

Tags

DTIC Thesaurus Topics

  • Adolescents
  • Biological Factors
  • Biostatistics
  • Cancer
  • Cell Physiological Processes
  • Clinical Trials
  • Data Management
  • Detection
  • Health Services
  • Imaging Techniques
  • Lung Cancer
  • Neoplasms
  • Oncology
  • Pleural Diseases
  • Proteins
  • Small Molecules
  • Statistical Analysis

Fields of Study

  • Medicine
  • Physics

Readers

  • Breast cancer cell signaling and growth regulation.
  • Medical Imaging.