Meningococcal Disease in US Military Personnel Before and after Adoption of Conjugate Vaccine
Abstract
During 2006-2013 only 1 military meningococcal case for which serogroup data are available (n = 28) was not serogroup C (n = 8), B (n = 8), or Y (n = 11). During that period, incidence in the US active-duty military of 0.271 cases per 100,000 person-years was not significantly different (p > 0.05) from that of 0.252 in the 2006-2012 age-matched (ages 17-64) US general population. During 2010-2013, military incidence was 0.173 cases per 100,000 person-years compared with 0.218 in the age-matched 2010-2012 US population. There was only 1 military case in 2011 and only 1 in 2012. The incidence of non-serogroup-B cases during the MPSV-4 era is estimated to have been 0.327 cases per 100,000 person-years. On the other hand, the incidence of non-serogroup-B cases during the MCV-4 era (counting only MCV-4- covered cases) 0.081. The difference between the MPSV-4 era and MCV-4 era incidence is significant (p < 0.05).
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 01, 2015
- Accession Number
- ADA617728
Entities
People
- Christopher Phillips
- Dennis J. Faix
- Michael P. Broderick
Organizations
- Naval Health Research Center