Tolerance to Central Hypovolemia: The Influence of Oscillations in Arterial Pressure and Cerebral Blood Velocity
Abstract
Higher oscillations of cerebral blood velocity and arterial pressure (AP) induced by breathing with inspiratory resistance are associated with delayed onset of symptoms and increased tolerance to central hypovolemia. We tested the hypothesis that subjects with high tolerance (HT) to central hypovolemia would display higher endogenous oscillations of cerebral blood velocity and AP at presyncope compared with subjects with low tolerance (LT). One-hundred thirty-five subjects were exposed to progressive lower body negative pressure (LBNP) until the presence of presyncopal symptoms.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2011
- Accession Number
- ADA618753
Entities
People
- Caroline A Rickards
- Kathy L. Ryan
- Victor A Convertino
- William H. Cooke
Organizations
- United States Army Institute of Surgical Research