Homeostatic and Circadian Abnormalities in Sleep and Arousal in Gulf War Syndrome

Abstract

The purpose of this study is to assess sleep and wake parameters in veterans of the first Gulf War who have fatigue and other symptoms compared with veterans who do not have fatigue utilizing novel assessment techniques including temperature and high density EEG. This research study is in the data collection phase and data analysis phase. The most significant finding in this study during the previous research period was that temperature curves, which are well-tied with sleep/wake and feelings of fatigue/alertness are showing different projections in veterans endorsing fatigue than those who do not. We are looking to tie this more closely with EEG data as well. The most significant findings in this current research period are exciting EEG data related to frontal activity in the active group of subjects endorsing fatigue compared to an age and sleep breathing matched control group of healthy subjects. The finds show marked broad band reduction in neural activity in clear region of the frontal cortex in all stages of NREM sleep.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2014
Accession Number
ADA619613

Entities

People

  • Giulio Tononi
  • Ruth Benca
  • Timothy M. Juergens

Organizations

  • University of Wisconsin–Madison

Tags

Communities of Interest

  • Biomedical
  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Abnormalities
  • Biomedical Research
  • Brain
  • Cognitive Impairment
  • Data Analysis
  • Data Processing
  • Data Science
  • Diseases And Disorders
  • Dyssomnias
  • Frequency
  • Frequency Bands
  • Melatonin
  • Persian Gulf Syndrome
  • Power Spectra
  • Sleep Deprivation
  • Sleep Disorders
  • Structural Integrity

Readers

  • Circadian Sleep-Wake Regulation and Chronobiology
  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.
  • Neuroscience